Department of Horticultural Science, College of Agriculture, University of Birjand
10.22034/hbsj.2024.367340.1178
Abstract
Apitherapy with bee venom Abstract Bee venom has a wide range of biological potential and its use in beekeeping is increasing rapidly. Bee products have a significant potential to strengthen the immune system and improve human health. Bee venom contains amphipathic peptides such as melittin and apamin, enzymes such as phospholipase A2 and bioamines including histamine and catecholamines. Also, recent studies have reported the identification of different classes of enzymes in bee venom, including esterases, proteases and peptidases, protease inhibitors and other important enzymes involved in carbohydrate metabolism. The therapeutic uses of bee venom include anti-inflammatory, analgesic, antimicrobial, antiviral, neuroprotective, anti-arthritic and anti-cancer activities. Additionally, bee venom has shown promising benefits against various types of cancer as well as antiviral activity, even against the challenging human immunodeficiency virus (HIV). The immunological properties of bee venom warrant ongoing research to reduce allergic reactions, ensuring safe and effective use in medical practice. Keywords: Apamin, Protein, Anticancer, Melittin.
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